br Inevitably this study has limitations For example the
Inevitably, this study has limitations. For example, the animal injection method as well as the quantity and frequency of DNT cell and gemcitabine treatments was not based on previously published models.
In summary, our study demonstrated that pancreatic cancer growth is significantly inhibited by DNT cells both in vivo and in vitro and that the Fas/FasL signaling pathway is involved in the mechanism of DNT cell cytotoxicity. More importantly, this research may provide a preclinical basis for DNT cell therapy for pancreatic cancer.
Conflicts of interest
The authors declare that they have no competing interests.
This present study was funded by the National Natural Science Foundation of China (grant no. 81071985) and the Anhui Province Science and Technology Projects Foundation (grant no. 10080703038).
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Journal of Ethnopharmacology
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Antiproliferative activity of ionic liquid-graviola fruit extract against human T breast cancer (MCF-7) cell lines using flow cytometry techniques