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br In corroboration with the above
2020-07-27
In corroboration with the above-described body of results, an in-verse correlation of pp53 expression to m6A modification with METTL3 was comparably observed in TP53-Dox cells upon immunofluorescence staining. Increased levels of pp53 displayed prominently in cell nuclei (green, pp53-Alexa Fluor 4
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Fluxametamide br In order to prove the
2020-07-27
In order to prove the superior performance of the MWCNT on the electrode surface, the CV of thionine immobilized on the GCE/MWCNT/His-rGO was compared with that on the GCE/His-rGO. As seen, the MWCNT/His-rGO/thionine biointerface possesses a larger CV current than the His-rGO/thionine biointerface
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br response to intracellular sterol depletion Aberrant SREBP
2020-07-26
response to intracellular sterol depletion. Aberrant SREBP2 expression and activity has been associated with PCa progression [15e17], suggesting that prostate tumors may be particularly dependent on cholesterol and other isoprenoid metabolites, and therefore vulnerable to HMGCR inhibition by st
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br Table br Associations between breast
2020-07-06
Table 3 Associations between breast and prostate cancer and occupational exposure to alkylphenolic compounds. Breast cancer Prostate cancer Never exposed to alkylphenolic compounds 1233 1101 Ref Ref 1103 764 Ref Ref Occasional and/or low intensity (scores 1 and 2d) Durati
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br di erent mechanisms of which one of
2020-07-06
different mechanisms, of which one of the most important mechanisms may be aerobic glycolysis [28,29]. Although the correlation between HK2 and tumorigenesis has been confirmed by mouse models [30], the specific mechanism by which HK2 mediates the development of colon cancer remains unclear. Cur
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br intensity of a collection of pixel values
2020-03-24
intensity of a collection of pixel values (22). At least two tex-ture features were chosen in all folds, whether features related to size were considered for feature selection or not. The tex-ture feature of Suramin hexasodium salt was selected in every fold, in each fea-ture selection scenari
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br Kang CY Halabi WJ Chaudhry OO Nguyen
2020-03-24
[7] Kang CY, Halabi WJ, Chaudhry OO, Nguyen V, Pigazzi A, Carmichael JC, et al. Risk factors for anastomotic leakage after anterior resection for rectal cancer. JAMA Surg 2013;148:65e71. [8] Zhou C, Wu XR, Liu XH, Chen YF, Ke J, He XW, et al. Male gender VH-298 associated with an increased risk
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br Small interfering RNA siRNA
2020-03-24
2.5. Small interfering RNA (siRNA) transfection and gene forced-expression To knockdown endogenous SMAD2, SMAD3, SMAD4, ALK4, SNAIL and SLUG, Trichostatin A (TSA) were transfected for 48 h with 50 nM ONTARGETplus NON-TARGETINGpool siRNA (control) or ONTARGETplus SMARTpool siRNA (Dharmacon, Laf
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Please cite this article as Mei D
2020-03-24
Please cite this article as: Mei D et al., Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer, Acta Pharmaceutica Sinica B, https://doi.org/10.1016/j.apsb.2019.03.006 + MODEL Figure 3 Active autophagy
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br Advances in Biological Regulation br journal homepage www
2020-03-24
Advances in Biological Regulation journal homepage: www.elsevier.com/locate/jbior ABCC3 is a novel target for the treatment of pancreatic cancer Aleksandra Adamskaa, Riccardo Ferrob, Rossano Lattanzioc, Emily Caponec, Alice Domenichinia, Verena Damianic, Giovanna Chiorinod, Begum Gokcen
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br B br Figure Constituents and Functions of the
2020-03-17
B Figure 2. Constituents and Functions of the Core Cancer Secretome (A) A heat-scatterplot presenting the log2FCs and corresponding significance (false discovery rate [FDR]-adjusted p values) for the 16 genes making up the top 1% of the non-directional core secretome. The color and size of t
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br Ki br K i br
2020-03-17
Ki K i K i K h h k k Stage 2 Ki H2 h h k k P h h Ste3 P Boundary condition of III kind 2 i w r i w r h h w k k Ste2 P h h k k P Fig. 7. Moving layer thickness 2 in stage2. Fig. 8. Moving layer
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br Dr Blanchard declares travel and accommodation fees from
2019-11-11
Dr. Blanchard declares travel and accommodation fees from Janssen Pharmaceuticals and Dr. O’Neil de-clares personal fees from Ipsen outside the submitted work. Dr. Neugut receives consultant fees from Otsuka Pharmaceuticals, United Biosource Corp, Hospira, and Eisai and EHE International. All othe
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br Total patients enrolled br Patients
2019-11-11
Total patients enrolled Patients still alive Patients who died (excluded) Preferred place of death (POD) Hospital/Facility Home No preference Excluded Hospital/ Home Hospital/ Home Facility Facility Overall matches: Fig. 1. Flowchart indicating analy
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br C D May et al
2019-10-29
[14] C.D. May, et al., Epithelial-mesenchymal transition and cancer stem cells: a dan- O. Bozickovic et al. Contents lists available at ScienceDirect Biosensors and Bioelectronics journal homepage: www.elsevier.com/locate/bios A novel triarylboron based ratiometric fluorescent probe